The CD38 antigen is a 45 kDa single chain type II integral membrane glycoprotein, with the NH2-terminus inside the cytoplasm. CD38 is an enzyme with several activities such as NAD glycohydrolase, ADP ribosylcyclase and cyclic ADP ribose hydrolase. CD38 is expressed on activated T and B lymphocytes, NK cells, monocytes, plasma cells and medullary thymocytes. CD38 depends on the differentiation and activation of the cell. In the B cell lineage, CD38 is expressed in early stages of B-cell ontogeny, lost during maturation and re-expressed upon terminal differentiation to plasma cells. CD38 is expressed on thymocytes and at a high level on activated T cells. Most mature resting lymphocytes of both B and T lineages do not express the CD38 antigen. CD38 is widely used as a marker to study T and B lymphocyte activation.
|Clone: T16||Isotype: IgG1 Mouse|
|Clone: LS198-4-3||Isotype: IgG1 Mouse|
Product Line Specifications
|Flow Product Line||IOTest|
|Item Specifications Referenced||B09683|
The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent.