Focus on the Science

The CytoFLEX platform has been used successfully in a variety of research areas.  Select publications are listed below illustrating the diversity of uses and interesting questions that researchers are using the CytoFLEX Flow Cytometer to answer.

Amnion-Epithelial-Cell-Derived Exosomes Demonstrate Physiologic State of Cell under Oxidative Stress.
Sheller S, Papaconstantinou J, Urrabaz-Garza R, Richardson L, Saade G, Salomon C, Menon R.
PLoS One. 2016 Jun 22;11(6):e0157614. doi: 10.1371/journal.pone.0157614.

Dysregulation of proinflammatory versus anti-inflammatory human TH17 cell functionalities in the autoinflammatory Schnitzler syndrome. 
Noster R, de Koning HD, Maier E, Prelog M, Lainka E, Zielinski CE.
J Allergy Clin Immunol. 2016 Oct;138(4):1161-1169.e6. doi: 10.1016/j.jaci.2015.12.1338.

Correlation of Surface Toll-Like Receptor 9 Expression with IL-17 Production in Neutrophils during Septic Peritonitis in Mice Induced by E. coli.
Ren Y, Hua L, Meng X, Xiao Y, Hao X, Guo S, Zhao P, Wang L, Dong B, Yu Y, Wang L.
Mediators Inflamm. 2016;2016:3296307. doi: 10.1155/2016/3296307.

CXCR2 is essential for cerebral endothelial activation and leukocyte recruitment during neuroinflammation. 
Wu F, Zhao Y, Jiao T, Shi D, Zhu X, Zhang M, Shi M, Zhou H.
J Neuroinflammation. 2015 May 21;12:98. doi: 10.1186/s12974-015-0316-6.

Peripheral blood microvesicles secretion is influenced by storage time, temperature, and anticoagulants. 
Wisgrill L, Lamm C, Hartmann J, Preißing F, Dragosits K, Bee A, Hell L, Thaler J, Ay C, Pabinger I, Berger A, Spittler A.
Cytometry A. 2016 Jul;89(7):663-72. doi: 10.1002/cyto.a.22892.

A blast without power – cell death induced by the tuberculosis-necrotizing toxin fails to elicit adequate immune responses.
Maueröder C, Chaurio RA, Dumych T, Podolska M, Lootsik MD, Culemann S, Friedrich RP, Bilyy R, Alexiou C, Schett G, Berens C, Herrmann M, Munoz LE.
Cell Death Differ. 2016 Jun;23(6):1016-25. doi: 10.1038/cdd.2016.4.

Extracellular vesicles from malignant effusions induce tumor cell migration: inhibitory effect of LMWH tinzaparin.  
Gamperl H, Plattfaut C, Freund A, Quecke T, Theophil F, Gieseler F.
Cell Biol Int. 2016 Oct;40(10):1050-61. doi: 10.1002/cbin.10645.

Identification of WOX Family Genes in Selaginella kraussiana for Studies on Stem Cells and Regeneration in Lycophytes.
Ge Y, Liu J, Zeng M, He J, Qin P, Huang H, Xu L.
Front Plant Sci. 2016 Feb 5;7:93. doi: 10.3389/fpls.2016.00093.

The contribution of apoptosis and necrosis in freezing injury of sea urchin embryonic cells.
Boroda AV, Kipryushina YO, Yakovlev KV, Odintsova NA.
Cryobiology. 2016 Aug;73(1):7-14. doi: 10.1016/j.cryobiol.2016.06.007.

Phosphorus Deficiency Inhibits Cell Division But Not Growth in the Dinoflagellate Amphidinium carterae. 
Li M, Shi X, Guo C, Lin S.
Front Microbiol. 2016 Jun 1;7:826. doi: 10.3389/fmicb.2016.00826.